What pain relievers can I take with Adderall?

We consider any debate regarding Adderall hypersensitive—its status as a stimulant, appetite-suppressing qualities, the potential for abuse, and the potential to cause severe derangement in the patient. This article will answer frequently asked questions about Adderall and its interaction with any prescribed pain reliever.

Adderall treats attention-deficit hyperactivity disorder (ADHD) and narcolepsy. Adderall consists of Amphetamine and Dextroamphetamine. These are central nervous system stimulants that impact neurotransmitters in the brain and nerves, which in turn cause hyperactivity and impulse control.

Can I take Aleve (Naproxen sodium) and Adderall?

Yes, of course! Adderall, an amphetamine, is a potent dopamine, serotonin, and norepinephrine reuptake inhibitor. This is what causes wakefulness, an increase in concentration, and euphoria at high doses.

Naproxen is an NSAID (Non-Steroidal Anti Inflammatory Drug), similar to aspirin and ibuprofen. NSAIDs inhibit COX-1 and COX-2, which are enzymes that help synthesize prostaglandins. By interfering with this process, NSAIDs help reduce inflammation, body temperature, clotting, and perceptions of pain.

As you can see, these drugs work in very different ways in different body areas. So you're totally safe taking both.

A-pak laboratories pediatric analgesic paracetamol

A-Pak laboratories pediatric analgesic Paracetamol is in the drug class miscellaneous analgesics. A-Pak laboratories pediatric analgesic Paracetamol is used to treat the following conditions:

  • Fever
  • Muscle pain
  • Pain
  • Sciatica

There are no such interactions detected between Adderall and Paracetamol. However, this does not imply that no interactions exist. Always seek the advice of your healthcare provider before using these two medications together.

Does Adderall interact with gabapentin?

Gabapentin and Adderall should be safe to take together. There are no known interactions between these medications.

Gabapentin is a medication to treat nerve pain and seizure disorders. Adderall may increase your chances of having a seizure. Therefore, before using Adderall, you should consult your doctor if you are taking gabapentin for a neurological issue. They can assess if it is safe to use these certain medications together. 

Does Adderall interact with ibuprofen?

Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) to alleviate pain caused by various illnesses, including headaches, tooth discomfort, menstrual cramps, muscle spasms, and arthritis. It also treats fevers, mild aches, and pains caused by the common cold or flu.

There are no such interactions detected between Adderall and Ibuprofen. However, this does not imply that no interactions exist. Always seek the advice of your healthcare provider before using these two medications together.

What is the essential information I must know about Adderall?

Do not use this drug if you have used an MAO inhibitor for 14 days. A fatal drug interaction might occur. MAO inhibitors include linezolid, isocarboxazid, rasagiline, methylene blue injection, phenelzine, agiline, selegiline, tranylcypromine, and others.

You may not use amphetamine and Dextroamphetamine if you have the following:

  • An allergy to any stimulant drug
  • High blood pressure, heart disease, and coronary artery disease
  • Glaucoma
  • Overactive thyroid
  • Severe anxiety, agitation, or tension (stimulant medicine can make these symptoms worse)
  • A history of drug or alcohol addiction

Be sure the doctor knows if you also take stimulant medication, opioid medicine, herbal products, or medication for depression, mental illness, migraine headaches, Parkinson's disease, serious infections, or prevention of nausea and vomiting. These medications may interact with Amphetamine and Dextroamphetamine and cause a severe condition, serotonin syndrome. Stimulants have caused heart attacks, stroke, and sudden death in certain peopleTell your doctor if you have the following:

  • High blood pressure
  • Heart problems or a congenital heart defect       
  • A family history of heart disease

To make sure this drug is safe, tell your doctor if you or anyone in the family has ever had the following:

  • Depression, bipolar disorder, psychosis, or suicidal thoughts or actions
  • Motor tics (muscle twitches) or Tourette's syndrome
  • Seizures or epilepsy
  • An abnormal brain wave test (EEG)
  • Kidney disease
  • Blood circulation problems in your hands or feet

Taking this medicine during pregnancy may cause premature delivery, low birth weight, or withdrawal symptoms in the newborn. Tell your doctor if you are already pregnant or planning to become pregnant. It will be best if you do not breastfeed while you are using this medicine.

Do not give this drug to a child without medical advice. Not every brand of amphetamine and Dextroamphetamine is for use in the same age group of children.


Adderall is a powerful stimulant that increases body temperature, blood pressure, and heart rate, keeping you alert and stimulated while restricting appetite. Regular usage or misuse of Adderall can cause structural changes in the brain and alter regulating emotions. Therefore, consult with a healthcare expert before taking Adderall with any pain reliever. Tell your doctor promptly if you take these medications and notice an abrupt interaction.