
What is Zolpidem?
Zolpidem is a prescription medication used to treat insomnia, or difficulty falling asleep and staying asleep, in adults. It is a sedative-hypnotic medication that works by slowing down the working of the central nervous system, helping to induce sleep.
In the United Kingdom, Zolpidem is a prescription-only medication. This means that it can only be obtained with a prescription from a healthcare expert and should be taken as directed by a healthcare provider. In addition, it is crucial to follow the instructions for taking Zolpidem carefully, as it can cause drowsiness and impair mental and physical abilities, which could be dangerous if driving or operating heavy machinery.
It is also important to note that Zolpidem should not be taken for long periods of time, as it can lead to dependence and withdrawal symptoms when stopped. Zolpidem should only be used as a short-term treatment for insomnia and not be used in combination with alcohol or other sedative medications. If you have any questions about Zolpidem or how to use it safely, you should speak with your healthcare provider.
What is Zolpidem used for?
Zolpidem is a medication used to treat insomnia, a condition characterised by difficulty falling or staying asleep. It belongs to a class of drugs which work by slowing down the central nervous system and helping people fall asleep. Moreover, the drug is available in the United Kingdom in both immediate-release and extended-release formulations.
The immediate-release formulation is taken just before bedtime. It is intended to help people fall asleep more quickly, while the extended-release formulation is taken once a day to help people stay asleep throughout the night.
Zolpidem is typically prescribed for short-term use, as chronic use of the medication can lead to dependence and withdrawal symptoms. It is generally used as a last resort for treating insomnia after other non-pharmacologic treatments, such as relaxation techniques and sleep hygiene measures, have been tried and found to be ineffective.
In addition to its use in the treatment of insomnia, Zolpidem may also be used off-label to treat other medical conditions, such as anxiety disorders and acute seizure episodes.
How does Zolpidem work?
Zolpidem is a medication that belongs to a class of drugs called sedative-hypnotics, used to treat insomnia and other sleep disorders. It works by binding to a specific type of receptor in the brain called the gamma-aminobutyric acid (GABA) receptor.
GABA is a neurotransmitter that plays a key role in the regulation of sleep and wakefulness. When GABA is released into the brain, it promotes relaxation and sleepiness by inhibiting the activity of certain neurons. Zolpidem enhances the effects of GABA by binding to a specific subtype of the GABA receptor and increasing the activity of this neurotransmitter.
In addition to its effects on GABA, Zolpidem may also tend to have effects on other neurotransmitter systems in the brain, such as serotonin and noradrenaline, which may contribute to its sedative and hypnotic effects.
How effective is Zolpidem?
In clinical trials, Zolpidem has been shown to be effective in improving sleep onset and sleep maintenance in people with insomnia. In addition, studies have found that Zolpidem significantly increased the time it took for people with insomnia to fall asleep and improved the overall quality of sleep compared to a placebo.
However, it is necessary to note that the effectiveness of Zolpidem may vary from person to person and may not work for everyone. In addition, Zolpidem is generally prescribed for short-term use, as chronic use of the medication can lead to dependence and withdrawal symptoms.
Overall, Zolpidem can be an effective treatment option for people with insomnia, but it may not work for everyone and should be used under the guidance of a healthcare provider. It is imperative to follow the dosing instructions a healthcare provider provides and not exceed the recommended dosage.
What are the side effects of Zolpidem?
Like all medications, Zolpidem can cause side effects in some people.
Common side effects of Zolpidem include:
- Drowsiness: Zolpidem can cause drowsiness, which may persist into the next day, especially if taken at a high dose or if the person has liver problems. This can affect the ability to perform tasks that require alertness, such as driving or operating heavy machinery.
- Headache: Some people may experience a headache after taking Zolpidem.
- Dry mouth: Zolpidem can cause dry mouth, which can lead to discomfort and an increased risk of tooth decay.
- Dizziness: Zolpidem can cause dizziness, which may cause a person to feel unsteady or lose balance.
- Nausea: Some people may experience nausea after taking Zolpidem.
Other less common side effects of Zolpidem include:
- Changes in appetite: Zolpidem may cause changes in appetite, leading to weight gain or loss.
- Changes in sex drive: Zolpidem may affect a person's sex drive or capability to perform sexually.
- Confusion: Zolpidem may cause confusion, especially in older people or those taking high doses.
- Memory problems: Zolpidem may cause memory problems, such as difficulty remembering events that occurred while taking the medication.
It is important to note that this is not a comprehensive list of all the possible side effects of Zolpidem and that everyone may not experience all of these side effects. If you experience any side effects while taking Zolpidem, it is important to report them to your healthcare provider. They can help you manage any side effects and determine if Zolpidem is the right treatment for you.
How to manage Zolpidem's side effects?
If you are taking Zolpidem and are experiencing side effects, there are a few things you can try to manage them:
- Talk to your healthcare provider: Your healthcare provider is the best source of information about managing Zolpidem's side effects. They may be able to recommend ways to reduce or eliminate the side effects you are experiencing.
- Take the medication as directed: It is imperative to follow the dosing directions provided by your healthcare provider and not exceed the recommended dosage. Taking more than the recommended Zolpidem dose can increase the side effects risk.
- Avoid activities that require alertness: Zolpidem can cause drowsiness, which may persist into the next day. Therefore, it is important to avoid activities that require alertness, such as driving or operating heavy machinery, while taking the medication.
- Practice good sleep hygiene: Maintaining good sleep hygiene habits, such as keeping a regular sleep schedule, avoiding caffeine and alcohol before bed, and creating a relaxing bedtime routine, may help to reduce the severity of side effects.
- Drink plenty of fluids: Dry mouth is a common side effect of Zolpidem. Drinking plenty of fluids, especially water, can help alleviate dry mouth and other associated symptoms.
- Eat a healthy diet: Eating a healthy diet rich in vegetables, fruits, and whole grains may help reduce the severity of side effects and improve overall health.
Overall, talking to your healthcare provider if you are experiencing side effects while taking Zolpidem is essential. They can help you determine the best course of action and whether Zolpidem is the right treatment.
Frequently Asked Questions
It is generally not recommended to take Zolpidem and Zopiclone together, as both medications belong to the same class of drugs called sedative-hypnotics and have similar mechanisms of action. Taking both medications together can increase the risk of side effects and may lead to an overdose.
In most countries, Zolpidem is available only with a prescription from a healthcare provider. It is not available over-the-counter (OTC) and cannot be purchased without a prescription.
Yes, Zolpidem can cause memory loss as a side effect. However, this is more likely to occur in people who take high doses of the medication or who use it for an extended period of time.
Stopping Zolpidem suddenly can cause withdrawal symptoms, such as tremors, sweating, and anxiety. To avoid these withdrawal symptoms, your healthcare provider may recommend a gradual reduction in dosage to allow your body to adjust to the change.
Zolpidem can cause heart palpitations as a side effect, although it is not a common occurrence. If you experience heart palpitations while taking Zolpidem, it is important to report this to your healthcare provider. They can help you determine the cause and whether Zolpidem is the right treatment.
On average, Zolpidem can take up to 6 to 9 hours to be fully metabolised and eliminated from your body.
On average, Zolpidem begins to work within 15 to 30 minutes. However, the full effects of the medication may not be felt for up to an hour.
In terms of potency, Zolpidem and Zopiclone are considered to be similarly effective in the treatment of insomnia. However, it is essential to note that Zolpidem and Zopiclone's effectiveness may vary from person to person and may not work for everyone.
To buy Zolpidem in the UK, you will need to visit a healthcare provider and discuss your sleep problems with them. If they determine that Zolpidem is an appropriate treatment option for you, they will write you a prescription. You can then take the prescription to a pharmacy or buy it online.
It is generally not recommended to take Zolpidem every night. Instead, people should use it on an as-needed basis, as directed by a healthcare provider, to help with sleep onset or sleep maintenance.
It is generally not recommended to drink alcohol while taking Zolpidem, as alcohol can increase the sedative effects of the medication and increase the risk of serious side effects. Taking Zolpidem and alcohol together can lead to severe drowsiness, impaired cognitive and motor functions, and an increased risk of falls and other accidents.
It is possible to overdose on Zolpidem, although it is generally not a life-threatening condition. Symptoms of a zolpidem overdose may include:
- Severe drowsiness,
- Difficulty breathing,
- Impaired cognitive and motor functions.
In severe cases, an overdose can lead to coma or even death, although this is rare.
Taking Zolpidem during pregnancy is generally not recommended, as the safety of the medication for use during pregnancy is not conclusive. In addition, some studies have suggested that Zolpidem may increase the risk of congenital disabilities when taken during the first trimester of pregnancy.
Some people may experience anxiety or nervousness as a side effect of Zolpidem, particularly when they first start taking the medication. However, this side effect is generally temporary and may resolve on its own after a few days of treatment.
It is possible that some people who take Zolpidem may experience an increase in blood pressure as a side effect of the medication. However, this is a rare side effect of Zolpidem, and it typically occurs in people who are taking high doses of the drug or who are sensitive to the effects of the medication.
There is no evidence to suggest that Zolpidem, a medication used to treat insomnia, can cause depression.
Constipation is not a common side effect of Zolpidem and is not listed as a known side effect in the drug's prescribing information. However, it is possible that some people who take Zolpidem may experience constipation as a result of other factors.
Hair loss is not a common side effect of Zolpidem and is not listed as a known side effect in the drug's prescribing information. However, it is possible that some people who take Zolpidem may experience hair loss as a result of other factors.
What Our Customers Say

This drug zolpidem has been like a benefit. I can go right to sleep whenever I take and get a usual 6- 9 hours.

Zolpidem is way better than any OTC drug, I've set up that when I take it, I sleep within 15 twinkles.
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